Job Description

About the Company :

Sino Biological Inc. is a world-renowned reagent supplier and contract research organization at the forefront of life sciences. With a strong foothold in the international market, we are listed on ChiNext of the Shenzhen Stock Exchange (301047 Sino Biological Inc.). Our pioneering technology platform is based on an in-house developed mammalian cell-based recombinant expression system, supported by proprietary reagents and processes. This enables us to achieve high-efficient production of antigens and antibodies, driving innovation and discovery in the field.

About the Role:

We are seeking a highly skilled Protein Purification Scientist to support downstream process development and purification of recombinant proteins and antibodies. This role will be responsible for executing purification workflows, performing analytical characterization, and ensuring high-quality deliverables in a fast-paced, client-driven environment.

Responsibilities

Downstream Processing & Chromatography

• Operate and maintain AKTA Pure systems using UNICORN software for protein and antibody purification
• Execute purification processes for proteins expressed in mammalian systems (HEK293, CHO)
• Apply chromatography techniques including:
• Affinity (IMAC, Protein A/G)
• Ion Exchange (IEX)
• Size Exclusion (SEC)
• Hydrophobic Interaction (HIC)
• Scale purification workflows from pilot to multi-liter production
• Perform column packing, optimization, and troubleshooting

Quality Control & Analytical Characterization

• Conduct protein analysis using SDS-PAGE and Western Blot
• Perform HPLC-SEC for protein purity and aggregation assessment
• Execute stability and binding assays including:
• Differential Scanning Fluorimetry (DSF)
• ELISA
• BLI
• Analyze and interpret data to support product quality and development

Documentation & Compliance

• Maintain accurate laboratory notebooks and experimental records
• Follow SOPs and ensure compliance with internal quality standards
• Support documentation required for traceability in a CRO/client-facing environment

Requirements

• Ph.D., Master’s, or Bachelor’s degree in Biochemistry, Molecular Biology, Biotechnology, or related field.
• Hands-on experience with protein purification and downstream processing
• Strong expertise in chromatography and analytical techniques listed above
• Experience working with mammalian expression systems preferred
• Prior experience in a CRO or fast-paced research environment is a plus
• Strong problem-solving and troubleshooting skills
• Ability to manage multiple projects and timelines
• Detail-oriented with a focus on quality and accuracy
• Effective communication and collaboration skills

Why Join Us at C4B?

Working at Sino Biological’s C4B facility isn’t just another lab job, it’s a chance to be part of something bigger. Here are just a few of the unique benefits of our Houston site:

• Opportunity to work on cutting-edge protein and antibody development
• Collaborative, high-impact scientific environment
• Growth opportunities within both technical and client-facing career paths
• World-class location: Be part of the Texas Medical Center, the largest medical complex in the world, where biotech innovation thrives.
• Beautiful work environment: Enjoy a brand-new, state-of-the-art facility designed for collaboration and scientific excellence.
• Free onsite parking: Skip the hassle and expense of parking in the Medical Center, we’ve got you covered.
• Free onsite gym: Stay active and energized with convenient access to fitness facilities right at work.
• Career growth opportunities: Learn directly from industry professionals while growing your career at a global biotech company.
• Supportive team culture: A welcoming, team-first workplace that values diversity, collaboration, and professional development.

Join Us in Advancing Scientific Innovation!

Be a part of Sino Biological and contribute to groundbreaking scientific advancements worldwide. Apply today to join our dynamic team!

Sino Biological is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

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